A recurrent de novo heterozygous missense variant, [c.155G>A p.(Arg52His)] of FGF12 has been reported in individuals with developmental and epileptic encephalopathy (DEE) and cerebellar atrophy (#617166; MIM) (Siekierska et al, 2016; Takeguchi et al, 2018). This evidence concerns the gene FGF12 and developmental and epileptic encephalopathy.