The GSCALite platform was used to analyze the DNA methylation differences of FCRL family genes between tumors and normal tissues in various cancers, and it was discovered that FCRL1-4 and A methylation were significantly down-regulated in LIHC, BLCA, LUSC, HNSC, BRCA, LUAD, PRAD, MESC, KIRC, and UCEC (Figure 4F). Here, FCRLA is linked to cancer.