However, in the case described, leptospirosis was identified as a cause of rhabdomyolysis; prospective or early identification of infectious or other known precipitants of rhabdomyolysis offers potential opportunity for treatment through inhibition of myoglobin uptake or cell injury, such as with cilastatin, a megalin inhibitor,S9 which is also thought to have broad AKI-protective properties.4 This evidence concerns the gene LRP2 and rhabdomyolysis.