ALK and neuroblastoma: Cargo included antisense oligonucleotides against proto-oncogene c-myb, which showed long-term survival (more than 120 days) of mice xenografted with human neuroblastoma 56, chemotherapeutic doxorubicin, which selectively inhibited growth and dissemination of human neuroblastoma in mice 57, and siRNA, which knocked down the gene for anaplastic lymphoma kinase (ALK) in neuroblastoma xenografted in mice, causing cell growth arrest, apoptosis, and prolonged survival 58.