Studies have used the peptide aptamer All-7, All-7 can specifically bind to the ErbB2 receptor, interfere with the activation of the AKT pathway Figure 1, and it cannot regulate the nuclear transcription factor κB (κB was first found in B lymphocytes because it binds to the B site of the immunoglobulin κ light chain gene enhancer and regulates the transcription of the immunoglobulin κ light chain, it is named nuclear transcription factor κB) and FOXO-1 through the phosphorylation of AKT, and restore the sensitivity of tumor cells to paclitaxel (Kunz et al., 2006). The gene discussed is AKT1; the disease is neoplasm.