Xie et al. (Xie et al., 2021b) showed that IGF2BP3 promotes Ndc80 kinetochore complex component (NUF2) expression and RCC progression by enhancing the stability of cyclin-dependent kinase inhibitor 2 B antisense 1 lncRNA (CDKN2B-AS1). The gene discussed is IGF2BP3; the disease is renal cell adenocarcinoma.