Subgroup analysis by ethnicity revealed a significant association of GSTP1 rs1138272 with COPD risk among Caucasians for the homozygote model (OR = 2.570, PZ = 0.112), heterozygote model (OR = 2.244, PZ = 0.009) dominant model (OR = 2.303, PZ = 0.009) and allele model (OR = 1.822, PZ = 0.000). Here, GSTP1 is linked to chronic obstructive pulmonary disease.