EPHX1 and chronic obstructive pulmonary disease: A previous meta-analysis of 19 studies published in 2016 by An L et al. did not find any association between EPHX1 rs1051740 and COPD risk in Asians (OR = 0.92, PZ=0.31) and Caucasians (OR = 1.01, PZ=0.65) (An et al., 2016b).