NOTCH2 and glioblastoma: These data were partly consistent with previous results that Notch signaling is highly expressed in the Classical subtype (Verhaak et al., 2010) Additionally, our results further demonstrated that the expression of Notch2 at mRNA or protein levels showed no relationship with patients’ prognosis, suggesting that Notch2 may play a minor role in the GBM initiation and progression.