In addition, in GRN, basic leucine zipper ATF-like transcription factor 3 (BATF3) has been shown to exhibit a regulatory role in MDSC subpopulations, and although the regulatory role of BATF3 in influenza A has been demonstrated (Lee et al., 2021), its role in ARDS has not been clarified. Here, BATF3 is linked to acute respiratory distress syndrome.