The comparisons of the HECDI, CDI, and control groups, no differences in the levels of IMP1, Koc, p62, RalA, Survivin, Zeta, NPM1, Cmyc, p53, HCC, and p16 are found to be statistically significant p < 0.05) (Tables 4.1-4.4). This evidence concerns the gene BIRC5 and hepatocellular carcinoma.