The comparisons of the HECDI, CDI, and control groups, no differences in the levels of IMP1, Koc, p62, RalA, Survivin, Zeta, NPM1, Cmyc, p53, HCC, and p16 are found to be statistically significant p < 0.05) (Tables 4.1-4.4). The gene discussed is NPM1; the disease is hepatocellular carcinoma.