In univariate analysis, the serum PSA (p < 0.001), mpMRI-based PSAD (p < 0.001), PI-RADSv2 score (p < 0.001), number of positive cores (p < 0.001), percentage of positive cores (p < 0.001), max core involvement (p < 0.001) and biopsy GG (p = 0.001) emerged as significant predictors of APCa. The gene discussed is KLK3; the disease is episodic ataxia type 2.