Compared with the normal group, the cryptozoospermia group (Fibrotic peritubular myoid cells, Perivascular cells, PMCs, Immune cells, and Macrophages) was mainly gathered in the process of IL-17 signaling pathway and coronavirus infection, while the normal group (Diplotene and Pachytene) was mainly concentrated in the process of male meiosis and spermatogenesis. Here, IL17A is linked to Cryptozoospermia.