The receiver operator characteristic curve (ROC) plotted by CYP2E1 content in normal brain tissue and adjacent tissue of glioma patients was used to predict the occurrence of glioma, which showed that the area under ROC curve (AUC) was 0.849 (95%CI, 0.768–0.941, p < 0.001), with a sensitivity of 87.1% and a specificity of 78.3% (Figure 1I). The gene discussed is CYP2E1; the disease is central nervous system cancer.