It is known that peroxisome proliferator‐activated receptor γ (PPAR‐γ) expression is distinctly upregulated in MES GBM, and provides insight into PPAR‐γ as a potential therapeutic target for patients with MES GBM.[76] Upregulation of CYP2E1 has been reported to increase PPAR‐γ expression,[77] which is supported by our results. The gene discussed is CYP2E1; the disease is glioblastoma.