Q11 does not directly affect tumor cells but blocks the tumor‐promoting effect of microglia/macrophage (M/Mφ) in the tumor microenvironment through PPARγ‐mediated activation of the STAT‐1 and NF‐κB pathways and inhibition of the STAT‐3 and STAT‐6 pathways. The gene discussed is PPARG; the disease is neoplasm.