POLRMT and neoplasm: We also found that the methylation state of POLRMT was lower in tumor samples than in normal samples (p = 0.023) (Figure 3B); this was negatively co‐related to the POLRMT expression level in TCGA‐LUAD (Pearson rho = −0.15, p < 0.001) and CPTAC datasets (Pearson rho = −0.07, p = 0.514) (Figure S2).