TGFB1 and cirrhosis of liver: BMSCs are derived from mammalian bone marrow, and their low immunogenic properties make them useful for autologous or allogeneic cell transplantation therapy.[4] BMSCs therapy has already been shown effective for liver cirrhosis.[5] Previous studies have shown that BMSCs could alleviate liver cirrhosis through multiple pathways, including homing,[6] differentiation into hepatocyte‐like stem cells,[7] paracrine hepatocyte growth factor execution,[8] and TGF‐β/SMAD pathway inhibition.[9] etc. The mechanism of BMSCs in the treating liver cirrhosis is being continuously investigated.