The results of the pathway analysis were in line with a hierarchical cluster analysis as shown in heatmaps indicating a marked up‐regulation of genes responsible for oxidative phosphorylation (Figure 3F) and fatty acid oxidation (Figure 3G) and a broad down‐regulation of genes involved in the NF‐κB pathway (Figure 3H), phagosome formation pathway (Figure S11A, Supporting Information) and hepatic fibrosis signaling pathway (Figure S11B, Supporting Information) in Dnmt1‐knockout hepatocytes. This evidence concerns the gene DNMT1 and Hepatic fibrosis.