TET2 and fatty liver disease: DNA demethylation can be made by a family of enzymes called the TETs including members TET1, TET2, and TET3 that are capable of removing the methyl group from 5‐methylcytosine.[6] To study the physiological significance of TETs in the development of HFD‐induced hepatic steatosis, we first determined whether HFD feeding alters Tets’ mRNA expression in the liver of mice.