LEPR and colorectal carcinoma: However, after adjustment for multiple testing, only LEP rs11763517 (Punadjusted = 0.001; Padjusted = 0.015), LEPR rs9436301 (Punadjusted = 0.000; Padjusted = 0.010), and LEPR rs7602 (Punadjusted = 0.000; Padjusted = 0.008) were associated with the DFS of CRC.