Therefore, this study revealed that, in general, the level of TF, microvascular density (MVD), angiogenesis, and VEGF-189 in lung cancer is reduced, but if the lung cancer progresses to advanced stages, such as NSCLC, and If cancer cells have a point mutation in the Ras gene, the expression of the abovementioned factors could be increased [174]. The gene discussed is TF; the disease is non-small cell lung carcinoma.