The present study showed that stimulation of LX-2 cells with TGF-β1, which is a typical profibrotic gene in the progression of hepatic fibrosis, downregulated the mRNA expression of miR-29a-3p and upregulated the level of Robo1 mRNA (Fig. 3A, B). The gene discussed is ROBO1; the disease is Hepatic fibrosis.