The epidermal growth factor receptor/extracellular signal-regulated kinase/p38/mitogen-activated protein kinase (EGFR/ERK/p38 MAPK) signaling pathway affects glioma proliferation and apoptosis [12], and AQP9 is involved in the oxidative phosphorylation pathway in glioma cells [13]. The gene discussed is WNK2; the disease is central nervous system cancer.