KRAS and neoplasm: In addition, GSEA analysis also indicated that hallmarks of tumor set were enriched in cell cycle-related pathways, such as MYC targets V1 and V2, E2F targets, and G2M checkpoint in the cluster 1, and cluster 2 enriched in apical surface, apical junction, myogenesis, KRAS signaling downregulated, EMT, UV response downregulated.