AKT1 and neoplasm: According to our results, the gene sets that promote tumor progression, including the JAK-STAT signaling pathway (hsa04630), NF-kappa B signaling pathway (hsa04064), PI3K-Akt signaling pathway (hsa04151), Ras signaling pathway (hsa04014) and MAPK signaling pathway (hsa04010), were significantly enriched in the high-risk group, while the process nucleotide biosynthesis (GO:0009165), regulation of DNA replication (GO:0006275), and cell cycle checkpoint (GO:0000075) were enriched in the low-risk group.