In the univariable models, preoperative BChE (p < 0.001), clinical tumor stage (p < 0.001), preoperative UICC classification (p < 0.001), grading (p < 0.001), pT (p < 0.001), pN (p < 0.017), and lymph node ratio (p < 0.001) were significantly associated with disease-free survival. This evidence concerns the gene BCHE and neoplasm.