PLOD1 and polycystic ovary syndrome: Indeed, others have shown that AMH may also directly regulate gonadotropins in the pituitary, increasing the LH/FSH ratio48–50, suggesting AMH could also cause infertility with a mechanism analogous to the anovulation observed in women with polycystic ovarian syndrome (PCOS), who also experience elevated AMH and high LH/FSH ratio51.