We therefore tested effects of gallic acid on Kv1.1/Kv1.2 heteromers generated in oocytes by co-injection of 1:1:2 parts Kv1.1:Kv1.1-E283K:Kv1.2 or Kv1.1:Kv1.1-L155P:Kv1.2 cRNA to approximate the Kv1.1/Kv1.2 heteromeric channel composition in EA1 patients heterozygous for either mutant KCNA1 allele. This evidence concerns the gene KCNA1 and episodic ataxia type 1.