The gallic acid augmentation of both wild-type and EA1-linked mutant Kv1.1 channel activity is of particular interest because gallic acid is present in the plants Native Americans used for ataxia therapy, it is a small molecule sold over the counter and used safely as a dietary supplement, and we found it was selective for Kv1.1 over Kv1.2 (Fig. 4). Here, KCNA1 is linked to cerebellar ataxia.