To elucidate the process of RPL10 ufmylation involved in pancreatic cancer cells, we used immunoprecipitation to examine the interactions between co-substrates RPL10 and UFM1 as well as between RPL10 and E3 ligase UFL1, which could be similar to the ufmylating modifications of ASC1 and RPL26 [12, 15, 16]. Here, RPL10 is linked to familial pancreatic carcinoma.