After adjusting for the potential blood eosinophil association confounders (P < 0.100) in Supplementary data online, Table S1, including smoking, diabetes, COPD, use of anti-platelet, angiotensin-converting enzyme inhibitor, and glucocorticoids, as well as high blood pressure, and obesity, blood eosinophil counts remained correlated significantly with the calcification scores of coronary artery (P = 0.017), aortic arch (P = 0.010), infrarenal artery (P = 0.011), and iliac artery (P = 0.009) (see Supplementary data online, Table S2). Here, ACE is linked to obesity due to melanocortin 4 receptor deficiency.