Blood eosinophil counts were significantly higher in the CVD mortality group than in those of total death (n = 13 482) or alive (n = 464 797).12 A sensitive marker of eosinophil activation, plasma ECP levels, was also significantly higher in patients with angiographic evidence of CAD such as stable angina and non-STEMI than those in patients with normal coronary arteries.13 In patients who received first generation drug-eluting stents, serum ECP levels were significantly higher in those who had MACE than in those without MACE during 18 month follow-up. The gene discussed is RNASE3; the disease is angina pectoris.