AGT and cardiac hypertrophy: Diet-induced experimental atherosclerosis took at least three months while left anterior-descending coronary artery ligation-induced MI,16 pressure overload- and β-adrenergic receptor agonist isoproterenol-induced cardiac hypertrophy,17 and peri-vascular CaCl2 injury or angiotensin-II perfusion-induced AAA18 occurred in less than 4 weeks.