Similarly, top candidate genes with differential CGI hypomethylation and corresponding increased mRNA expression in PCa compared to benign tissues are XPOT, MARS, METTL1, XPO5, EIF2A, MTHFD2, MTHFD1L, MTHFD2L, EIF5A, and SEC61A1. Here, METTL1 is linked to posterior cortical atrophy.