TBX21 and neoplasm: Mice that received control NK cells had minimal bioluminescent imaging signals on day 7 and day 10 after tumor challenge, while mice that received TBX21- or EOMES-single-edited or T+E edited NK cells had significantly higher tumor burden than those that received control NK cells (Figure 1, F and G), indicating reduced NK cell antitumor response in the absence of T-BET and/or EOMES.