SERPINB3 and neoplasm: The patient and tumor characteristics of this cohort have been previously described and are summarized in Supplemental Table 1; supplemental material available online with this article; https://doi.org/10.1172/JCI163841DS1 Patients were divided into 3 groups on the basis of their distribution of SERPINB3 transcript levels: SERPINB3-low (B3/L, n = 22), SERPINB3-intermediate (B3/Int, n = 22), and SERPINB3-high (B3/H, n = 22) groups (Figure 1A).