Albumin infusions could also decrease the mortality for hypoalbuminemia patients with SAP due to the various physiological roles of albumin, such as maintaining an effective plasma colloid osmotic pressure, binding with endogenous and exogenous substances, scavenging free radicals as an antioxidant, causing anticoagulant effects, and maintaining the acid base status and anti-inflammatory effects [26, 45]. This evidence concerns the gene ALB and Hypoalbuminemia.