FAP+CAFs promote the progression of various cancers, including gastric cancer [16], non-small cell lung cancer [17], prostate cancer [18], esophageal adenocarcinoma [19], clear cell renal cell carcinomas [20], ovarian cancer [21], and high-grade invasive urothelial carcinoma of the bladder [22]. This evidence concerns the gene FAP and Familial prostate cancer.