TWIST1 and neoplasm: The results suggested that largerer tumor size (OR=4.397, p = 0.026), higher ypT stage (OR=6.260, p = 0.036), higher expression of FAP in CAF (OR=16.905, p = 0.004), and higher expression of Twist1 (OR=14.238, p = 0.001) were independent predictors for the pathological response, respectively (Table 4).