IFNAR2 and Dravet syndrome: The B6.129S7-Dp(16Lipi-Zbtb21)1Yey/J mouse model of DS, herein ‘Dp16’, carries a segmental duplication of mouse chromosome 16 (MMU16) causing triplication of ~120 protein-coding genes orthologous to those on HSA21, including the Ifnr cluster15,16.