IRF8 and multiple sclerosis: We found evidence for colocalization for IRF8 in monocytes after 6h exposure to N. meningitidis and S. aureus with multiple sclerosis (H4,Nm = 0.997, H4,Sa = 0.997) and systemic lupus erythematosus (H4,Nm = 0.989, H4,Sa = 0.990), but only moderate evidence with inflammatory bowel disease (H4,Nm = 0.577, H4,Sa = 0.616).