Thus, the pathways “ILK Signaling”, “Osteoarthritis Pathway”, “Paxillin Signaling”, “Axonal Guidance” and “Cardiac Hypertrophy Signaling” were in the top 12 canonical pathways for both datasets, with a number of genes displaying the same directional change for TashAT2 and infection, such as the ILK pathway in which 6 of 10 genes (ITGB5, ITGB7, LEF1, PARVB, VCL and VIM) behave in the same manner (S7 and S8 Files). Here, VCL is linked to infection.