USP9X and cancer: Furthermore, specific members of the FAM gene family have been recognized as promising therapeutic targets and/or prognostic biomarkers for the management of multiple types of cancer, such as Glioblastoma multiforme (Rahane et al., 2019), Lung adenocarcinoma (Yu et al., 2020) and Colon adenocarcinoma (Wang et al., 2020a).