PLAU and colorectal carcinoma: The upregulation of other key TTSPs, such as tissue‐type plasminogen activator, urokinase-type plasminogen activator, plasminogen activator inhibitor type‐1, and others, play an essential role in CRC tumorigenesis (Heissig et al., 2021; Sakamoto et al., 2021; Zhai et al., 2022).