LYZ and acquired epidermolysis bullosa: Although an effect of lysozyme, a glycoside hydrolase that catalyzes the hydrolysis of the β-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine, on the pathogenesis of EBA seems unlikely, and LysMcre mice showed a similar response to WT animals in an LPS-induced model of sterile acute lung injury (64), an influence of the LysMcre allele on disease progression in the EBA model cannot be completely excluded.