Figure 4D shows that they are predominantly enriched in processes such as protein methylation, histone deacetylation, histone modification, and histone demethylation. The six genes with the highest Maximum Clique Centrality (MCC) score, such as KDM6B, KDM5A, SETD7, SUZ12, HDAC2, and CHD4, were regarded as the IPF hub genes (Figure 4E, Table 2). The gene discussed is HDAC2; the disease is idiopathic pulmonary fibrosis.