After exploring the three-dimensional structure of ARNTL2, it was observed that ARNTL2 amplification accounted for the largest proportion among all mutation types, with the highest amplification being observed in ovarian serous cystadenocarcinoma (7.53%), followed by TGCT (7.38%) and cervical squamous cell carcinoma (5.49%). The gene discussed is BMAL2; the disease is ovarian serous cystadenocarcinoma.