Experimental studies have shown that Golgi membrane protein 1 (GOLM1) is significantly upregulated in carbon tetrachloride (CCL4) induced mouse liver fibrosis, and GOML1 induces PD-L1 expression and promotes fibrosis by activating EGFR/AKT/STAT3 signaling pathway (175). The gene discussed is AKT1; the disease is Hepatic fibrosis.