RAB27A and Griscelli disease type 2: In the latter case, the mutated proteins include the SNARE protein, syntaxin11 (STX11, FHL 4) (96), and three tethering/priming factors Rab27a (RAB27A, Griscelli syndrome type 2), Munc13-4 (UNC13D, FHL 3) and Munc18-2 (STXBP2, FHL 5) (97–100).