↑ levels of Tβ4 in pSS compared to other subgroups. Tβ10 detectable in 66,7% of pSS subjects and 42,9% of sSS/SSc patients. Tβ4 sulfoxide detectable in 44,4% of pSS patients and 42,9% of sSS/SSc patients. Tβ4 and Tβ10 not detectable in non-ss associated patients and HC. All patients had immunoreactivity for Tβ10. Tβ4 immunoreactivity was absent in pSS and sSS/RA-patients, but present in sSS/SSc and sSS/SLE-patients. In pSS, salivary Tβ expression was generally overexpressed. Here, TMSB10 is linked to systemic sclerosis.