SS is associated with the human leukocyte antigen (HLA) class II types DR3 and DR2, particularly the DRB1*03/DQB1*02 and DRB1*15/DQB1*01 haplotypes, but only in patients having serum autoantibodies against SSA/Ro and SSB/La antigens (11–13). Here, CALR is linked to synovial sarcoma.