No significant difference in salivary miRNA expression between patients and HC. Patients with SS had higher expression of salivary miR146a than HC. Salivary miR146b was significantly more expressed in the ptt. with worse ESSPRI scores (p=0.02), whereas salivary miR17 and 146b and plasma miR17 expression was ↓ in the patients with higher ultrasound scores (respectively p=0.01, p=0.01 and p=0.04). Salivary miR18a expression was significantly ↑ in the patients who were anti-La/SSB positive (p=0.04). Neither salivary nor plasma miRNAs correlated with disease duration or concomitant therapies. Here, SSB is linked to synovial sarcoma.