HSPA5 and familial pancreatic carcinoma: DnaJ Heat Shock Protein Family (Hsp40) Member B11 (DNAJB11), a co-chaperone of HSPA5/BiP/GRP78 (33), was reported to promote the development of pancreatic cancer cells in vitro and in vivo by upregulating the HSPA5 expression and activating EGFR/MAPK pathway (34).