Notably, since CCR4 expresses not only CTCL cells, but also skin‐homing T cells including CD8+ T cells and regulatory T cells (Tregs),7, 8 bexarotene might modulate the profiles of tumour‐infiltrating lymphocytes (TILs) to induce an anti‐CTCL immune response in CTCL patients. This evidence concerns the gene CCR4 and neoplasm.