IGHE and atopic eczema: For example, patients with atopic dermatitis, a chronic inflammatory skin disease associated with an IgE-mediated allergic response (Bieber, 2008; Werfel, 2009), are at elevated risk to be colonized with S. aureus and therefore often suffer from local infections of the skin (Geoghegan et al., 2018; Ogonowska et al., 2020).