The mean fluorescent intensities (MFI) for the expression of negative control and CNPase from HOG cell-line (the quantitative analysis for Fig. 1A and B) is shown in Supplementary Fig. 5A, while the MFI for antibodies from control and MS patients’ CSF (the quantitative analysis for Fig. 1C and D) binding to HOG cell-line is shown in Supplementary Fig. 5B. Here, CNP is linked to myeloid sarcoma.