The methylation site cg21033440 upstream of KCNK7 contributed to hypertension (β = 0.01, p = 3.8e−11, Supplementary Table S4) by increasing the expression of this gene (β = 0.14, p = 8.9e−8, Supplementary Table S3). This evidence concerns the gene KCNK7 and Hypertension.