NRBP1 and type 2 diabetes mellitus: As presented in Figure 5A, mQTLs for cg20102877 showed congruence with eQTLs for NRBP1 but not with eQTLs for KRTCAP3. As a result, higher methylation at cg20102877 site contributes to the risk of T2D by increasing the expression of NRBP1 but lowering the level of KRTCAP3 (Figure 5B).