CD79A and typhoid fever: Anti-HlyE immunoglobulin A (IgA) antibodies, alone or in combination with anti-LPS IgA antibodies, were found to have high sensitivity and specificity (>90%) to distinguish acute typhoid infection from other invasive bacteremias in febrile patients in Bangladesh and Nepal; these same antigens were significantly elevated in Bangladeshi typhoid cases compared to healthy controls [18].