CRP and inflammatory bowel disease: In the GEMINILTS trial, improvements in P-CRP concentrations were observed in patients with CD.38 Improved P-CRP levels have been observed in long-term follow-ups of somereal-world cohorts of VDZ-treated patients with CD and UC.26,41 Still, most studies havefailed to demonstrate a link between VDZ treatment and improvements in P-CRP concentrations23, or they have only observed an improvement in patients with CD.25 Long-term data on f-calprotectin in IBD patients treated with VDZ arelimited.